Long Term Medical Treatment of Congenital Hyperinsulinaemic Hypoglycaemia
نویسندگان
چکیده
1Department of Endocrinology, King Faisal Specialist Hospital and Research Centre Jeddah, Saudi Arabia 2Department of Paediatric Endocrinology, British Columbia Children Hospital Vancouver, Canada 3Department of Paediatrics, University of British Columbia, Consultant Paediatric Endocrinologist British Columbia Children Hospital Vancouver, Canada Journal of Endocrinology and Diabetes Open Access Research Article
منابع مشابه
Diagnosis and management of hyperinsulinaemic hypoglycaemia of infancy.
Hyperinsulinaemic hypoglycaemia is a cause of persistent hypoglycaemia in the neonatal and infancy periods. Prompt recognition and management of patients with hyperinsulinaemic hypoglycaemia are essential, if brain damage and long-term neurological sequelae are to be avoided. Hyperinsulinaemic hypoglycaemia can be transient, prolonged, or persistent (congenital). Advances in the fields of molec...
متن کاملHyperinsulinaemic hypoglycaemia in small for dates babies.
Blood glucose concentrations were measured prospectively in 27 small for dates infants in the first 48 hours after birth: 10 infants became hypoglycaemic. Of these, five had inappropriately raised plasma insulin concentrations. Plasma free fatty acids were lower and carbohydrate intake higher in these five infants, further supporting the diagnosis of hyperinsulinism. The hypoglycaemia recurred ...
متن کاملHyperinsulinaemic hypoglycaemia in small for dates babies
Blood glucose concentrations were measured prospectively in 27 small for dates infants in the first 48 hours after birth: 10 infants became hypoglycaemic. Of these, five had inappropriately raised plasma insulin concentrations. Plasma free fatty acids were lower and carbohydrate intake higher in these five infants, further supporting the diagnosis of hyperinsulinism. The hypoglycaemia recurred ...
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Congenital hyperinsulinaemic hypoglycaemia (HH) can occur in isolation or it may present as part of a wider syndrome. For approximately 40%-50% of individuals with this condition, sequence analysis of the known HH genes identifies a causative mutation. Identifying the underlying genetic aetiology in the remaining cases is important as a genetic diagnosis will inform on recurrence risk, may guid...
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Persistent hyperinsulinaemic hypoglycaemia of infancy (PHHI) is an uncommon condition that leads to hypoglycaemia in newborn or infancy. The responsible lesion can be either focal or diffuse within the pancreas. Being a rare disease entity in our locality, we describe our experience in managing an infant with focal PHHI that could not be localised by pre-operative investigations. Furthermore, a...
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